Process Development Engineer I - Upstream Viral Vector Development

Profile

The Preclinical Manufacturing and Process Development group (PMPD) is looking for a Process Development Engineer: Upstream, responsible for upstream development efforts to support manufacturing process development functions. This individual will work as part of a multi-functional team to provide Adeno-Associated Virus (AAV) manufacturing processes and products with the aim of providing treatment to unmet medical needs through gene therapy. This is a growth opportunity that combines the excitement and opportunity of a start-up with the security and institution knowledge gained from working for a larger firm.

A Typical Day in the Role Might Look Like:

• As part of the viral vector process development team, design optimized, characterized and robust seed train and bioreactor processes for the upstream production of viral vectors in suspension cell lines suitable for future GMP clinical production.
• Support the optimization of transfection and bioreactor parameters for viral production using multivariate design of experiment approaches.
• Conduct technology development studies aimed at enhancing the understanding of or improving viral production process.
• Cross-train on and provide support for analytical and downstream operations.
• Develop expertise in theory and practice of manufacturing steps and analytical methods.
• Support the customization of LIMS system and data visualization system for viral production.
• Documents experiments, results, and findings in electronic laboratory notebook; presents work at group and department meetings. Maintain instruments and troubleshoots instrumental/experimental problems.
• Support of weekend or off-hour experimental and pilot scale work, as required.

This Role Might Be For You If You:

• A strong fundamental understanding of the principles of upstream process development.
• History of developing upstream steps within bioprocesses.
• Experience with bioreactor scale up and operations.
• Excellent interpersonal, verbal and written communication skills.
• Must have strong initiative and drive to complete challenging tasks and learn new technologies.
• Must be capable of multi-tasking, working both independently and within a team environment.

This position requires a Bachelor’s and/or Master’s degree in either Chemical Engineering, Biochemical Engineering, Biochemistry, or related field. The extent of the candidate’s prior experience will determine the grade of the position. The ideal candidate would have experience with some of the following systems : NOVA FLEX, AMBR250 bioreactors, Bench top bioreactors, Single-use bioreactors (50-500 L), Biosafety cabinets, incubators, autoclave, Rockwell RSView32, Pi Historian, JMP, LIMS. Prior experience with producing AAV-based gene therapies is a plus. This job will periodically require short duration physical exertions, including light-medium weight lifting.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

,identifier:{name:**MEMBERS ONLY**SIGN UP NOW***.,value:REGEA0026R9556,@type:PropertyValue},datePosted:2022-03-02T03:42:33 00:00,validThrough:2022-04-01T03:59:59 00:00,employmentType:FULL_TIME,hiringOrganization:{name:**MEMBERS ONLY**SIGN UP NOW***.,@id:395032,url:****New York,address:{addressCountry:US,addressLocality:New York,addressRegion:New York,postalCode:10591,@type:PostalAddress},@type:place},industry:Engineering, Manufacturing & Production, Process,workHours:Full time,educationRequirements:Bachelors Degree,@type:JobPosting,@context:****

Company info

Sign Up Now - ChemistryCrossing.com